BIA  Laboratory

Biopolymers, Interactions and Assembly UR INRA 1268

The Biopolymers, Interactions and Assembly (BIA) belongs to the national research Institute for agronomical research (INRA) and is located in Nantes. The unit is composed by 8 thematic teams, one team that is an instrumental platform recognized at the national level by the IBISA label and several experimental facilities dedicated to: extraction/purification of proteins, production of recombinants antibodies and one facility for designing and constructing homemade scientific devices.

The scientific project of the BIA unit aims to understand the organization of biopolymers (proteins, polysaccharides, polyphenols) in the biomass and in the associated transformed products (food and non food applications). Regarding non-food applications, the aim of the unit is to optimize the valorisation of biomass (from agricultural of forestry production, co-products of fractionation process or waste) either in substitution of petrol based products or for the production of molecules of interest or biobased materials by using sustainable processes.


The unit projects are organized along the following axes:

  • Understand the construction process, organization and dynamics of biopolymers within the biomass in relation with their biological functions in planta and their functionality.
  • Fractionate or elaborate new biobased building blocks to drive the self-assembly processes in order to implement new functional materials
  • Understand physical chemistry basic for the elaboration of new biobased materials to optimize, modify and tune their functionality
  • Model the interaction and functions of biological systems or processes by mimetic assemblies

The skills of the unit are internationally recognized and are focused of the physical-chemistry of biopolymers, plant biochemistry and knowledge of the plant raw materials architecture, food and biobased materials structure and their evolutions during transformation (biologic, chemical, mechanical, …). The construction of model describing the structure and the evolution of their properties are fully integrate in the project of the unit. The technical tools available in the unit facilities and in the BIBS platform allow to investigate raw and processed materials at different length scales form the nano, micro and up to macroscales.

The unit has published more than 200 hundred papers and fill 5 patent applications during the period of 2014-2015.


Selected publications: 

  • Ray S., Vigouroux J., Quémener B., Bonnin E., Lahaye M. (2014). Novel and diverse fine structures in LiCl-DMSO extracted apple hemicelluloses. Carbohydrate Polymers, 108, 46-57. http://dx.doi.org/10.1016/j.carbpol.2014.03.017
  • Ying R., Saulnier L., Bouchet B., Barron C., Ji S., Rondeau-Mouro C. (2015). Multiscale characterization of arabinoxylan and β-glucan composite films. Carbohydrate Polymers, 122, 248. http://dx.doi.org/10.1016/j.carbpol.2015.01.014
  • Velasquez D., Pavon-Djavid G., Chaunier L., Meddahi-Pellé A., Lourdin D. (2015). Effect of Crystallinity, Plasticizer Content and Botanical Origin of Starch-Based Materials on Mechanical Properties and In Vivo Tissue Integration, Carbohydrate Polymers, 124, 180-187, http://dx.doi.org/10.1016/j.carbpol.2015.02.006
  • Cunha A.G., Mougel J.B., Cathala B., Berglund L.A., Capron I. (2014). Preparation of Double Pickering Emulsions Stabilized by Chemically Tailored Nanocelluloses. Langmuir, 30(31), 9327-9335. http://dx.doi.org/10.1021/la5017577
  • Dammak A., Quemener B., Bonnin E., Alvarado C., Bouchet B., Villares A., Moreau C., & Cathala B.(2015). Exploring Architecture of Xyloglucan Cellulose Nanocrystal Complexes through Enzyme Susceptibility at Different Adsorption Regimes. Biomacromolecules, 16(2), 589-596. http://dx.doi.org/10.1021/bm5016317